Journal: iScience
Article Title: Benzyl isothiocyanate suppresses development of thyroid carcinoma by regulating both autophagy and apoptosis pathway
doi: 10.1016/j.isci.2024.110796
Figure Lengend Snippet: Effect of BITC on S100 expression in an orthotopic model of ATC (A, B, D, and E) The immunohistochemical assay revealed a significant increase of S100 expression in the ATC group (B) compared to Sham mice (A); this expression was reduced following treatment with BITC at doses of 5 mg/kg (C),10 mg/kg (D) and 30 mg/kg (E) compared to ATC group (B) (see score F). The data are representative of at least three independent experiments. The sections were observed and photographed at 20× magnification. Values are means ± SEM. One-way ANOVA test followed by Bonferroni post hoc test for multiple comparisons. ∗∗∗ p < 0.001 vs. Sham; # p < 0.05 vs. ATC.
Article Snippet: Immunohistochemical localization for E-Cadherin (1:100; sc-8426 Santa Cruz Biotechnology, Dallas, TX), N-Cadherin (1:100; sc-8424 Santa Cruz Biotechnology, Dallas, TX), and S100 antibodies (1:100; sc-393919 Santa Cruz Biotechnology, Dallas, TX), was made as previously described.
Techniques: Expressing, Immunohistochemical staining